A composition for the treatment of sensitive teeth comprising a desensitizing amount of: a substrate treated with a desensitizing agent, wherein substrate acts as a delivery vehicle of therapeutic agents for the treatment of hypersensitive teeth and said desensitizing agent is coated or adsorbed on the surface or attached to the surface of the substrate by chemical, electrostatic or ionic bonds; and/or b) encapsulated or impregnated within the substrate.