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Heterocyclic amides useful as protein modulators
专利权人:
GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED
发明人:
Charnley, Adam,Dong, Xiaoyang,Ramanjulu, Joshi,Mehlmann, John,Darcy, Michael G.,Dodson, Jason W.,Hughes, Terry V.,Kang, Jianxing,Leister, Lara Kathryn,Li, Yue,Nevins, Neysa,Romano, Joseph J.,Wang, Gre
申请号:
NZ74595717
公开号:
NZ745957A
申请日:
2017.04.05
申请国别(地区):
NZ
年份:
2020
代理人:
摘要:
Disclosed is a compound which is (E)-1-(4-(5-carbamoyl-2-(1-ethyl-3-methyl-1H-pyrazole-5-carboxamido)-7-(3-morpholinopropoxy)-1H-benzo[d]imidazol-1-yl)but-2-en-1-yl)-2-(1-ethyl-3-methyl-1H-pyrazole-5-carboxamido)-7-methoxy-1H-benzo[d]imidazole-5-carboxamide or a tautomer thereof, or a pharmaceutically acceptable salt thereof, or a hydrate thereof; and a pharmaceutical composition comprising and a use of said compound for the treatment of STING (Stimulator of Interferon Genes) mediated disease such as various cancers.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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