Michiel Luc, Maria Van Gool,Manuel Jesús Alcázar-Vaca,Sergio-Alvar Alonso-de Diego,Ana Isabel De Lucas Olivares
申请号：
US15533308
公开号：
US20170369493A1
申请日:
2015.12.02
申请国别(地区):
US
年份:
2017
代理人:
摘要：
The present invention relates to novel 6,7-dihydropyrazolo[1,5-a]pyrazin-4(5H)-one derivatives as negative allosteric modulators (NAMs) of the metabotropic glutamate receptor subtype 2 (“mGluR2”). The invention is also directed to pharmaceutical compositions comprising such compounds, to processes for preparing such compounds and compositions, and to the use of such compounds and compositions for the prevention or treatment of disorders in which the mGluR2 subtype of metabotropic receptors is involved.
