The present invention is directed to a combination comprising a proteasome inhibitor and a compound of formula I or a pharmaceutically acceptable salt thereof: to a pharmaceutical composition and to a kit both comprising said combination, to the combination, composition or kit for use in the treatment of cancer, and to a method of treatment of cancer in a patient in need thereof comprising administering to said patient an effective amount of said combination, composition or kit.本發明係有關一種組合，其包含蛋白酶體抑制劑及式I化合物或其醫藥學上可接受之鹽：有關一種包含該組合之醫藥組成物及有關一種包含該組合之套組，有關用於治療癌症的該組合、組成物或套組，以及有關一種治療有需要之患者之癌症的方法，該方法包含向該患者投予有效量之該組合、組成物或套組。
