ANN AND ROBERT H. LURIE CHILDREN'S HOSPITAL OF CHICAGO
发明人:
Ann Harris,Lindsay R. Stolzenburg
申请号:
US15235682
公开号:
US09856481B2
申请日:
2016.08.12
申请国别(地区):
US
年份:
2018
代理人:
摘要:
Provided herein are microRNAs that target transforming growth factor beta (TGF-β) receptors and attenuate pathways of fibrosis. In particular, microRNA-1343 reduces expression of TGFBR1 and TGFBR2, decreases TGF-β signaling, represses pathways of fibrosis, and treats fibrotic diseases.