A clip applying apparatus is provided for applying a ligating clip to tissue. The clip applying apparatus includes, inter alia, a handle assembly, a central body portion, an anvil jaw, and a slide member movably supported in relation to the anvil jaw. The anvil jaw and the slide member are configured to define an enclosed tissue receiving area when the slide member is in an advanced position. A method is also provided for ligating tissue using the presently disclosed clip applying apparatus.