The present invention relates to an eye drop composition for treating keratoconjunctivitis containing hydrophilic sulfasalazine and hyaluronic acid. The eye drop composition for treating keratoconjunctivitis contains the hydrophilic sulfasalazine having a density of 0.005-0.1 %(w/v), hyaluronic acid having a density of 0.01-0.5 %(w/v), and also a carrier including an aqueous solution. The carrier including the aqueous solution is selected from a group, constituted by distilled water, phosphate buffer, a balanced salt solution and a saline solution, and is pharmaceutically acceptable.COPYRIGHT KIPO 2014본 발명은 친수성 설파살라진 및 히알루론산을 포함하는 각결막염 치료용 조성물 및 이의 제조 방법에 관한 것이다.