CRYSTAL STRUCTURE OF CRIg AND C3b:CRIg COMPLEX

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专利权人:

GENENTECH; INC.

发明人:

KATSCHKE, KENNETH, JR

申请号：

NZ57317607

公开号：

NZ573176A

申请日:

2007.05.30

申请国别(地区):

NZ

年份:

2012

代理人:

摘要：

Disclosed in the crystal structure of the marcrophage specific receptor (CRIg) having the amino acid sequence SEQ ID NO: 2. Also disclosed is the crystal structures of CRIg in complex with the C3b and C3c subunits of the complement C3 protein. The crystal structures are used to identify CRIg agonists that mimics the C3b binding.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/