Product sleeve includes product bottle for radionuclide, it has individual radiation shield with permeable lid and by radiation shield and filling sleeve, filling box is supported adjacent permeable lid by coupling the filling box of radiation shield into the bottle of radiation shield product, it is moveable in filling box, the filling box of the radiation shield is to engage and puncture permeable cover in product bottle during filling, filling box includes that the end opposite product bottle in aperture receives a radionuclide, scavenger that remove heavy metal from the radionuclide and a kind of filter, filter biological pollutant, product bottle is discharged simultaneously as radionuclide and passes through filling box and product bottle from hole.