A coupling device (1) for the connection of two ends (3, 9) of respective tubularmembers (2, 5), allowing the contact of the flowing fluid only with elements insidea closed container, circumstances and an inherently easy connection operation,thus it can be carried out, comprising: a closed container (10) housing said ends(3, 9) of respective tubular members (2, 5), one of said tubular members havinga flexible terminal section (8) thereof inside said closed container； a mobileconnection member (15), coupled at the end of said flexible terminal section(8), having a nozzle (16) apt to be inserted within a receiving end of the othertubular member,- and a cam device, located inside said closed container (10)and apt to be actuated from the outside of said closed container, apt to cooperatewith said mobile connection member (15), the cam device causing the insertionand the ejection of said nozzle in and from said receiving end, and the correspondingconnection and the disconnection of the two ends.
