Disclosed is an ex vivo method for increasing the effectiveness of antigen presentation by an isolated antigen presenting cell comprising the step of providing an isolated dendritic cell asialoglycoprotein receptor (DC-ASGPR) specific antibody or functional fragment thereof to which an antigen is attached, the antigen characterized in that it comprises at least one bacterial, viral, fungal, protozoan or cancer antigen, wherein neither the antigen nor the DC-ASGPR specific antibody or functional fragment thereof is attached to a Cohesin or Dockerin and contacting the isolated antigen presenting cell with the DC-ASGPR-specific antibody or functional fragment and antigen, wherein the antigen is processed and presented by the dendritic cell that has been contacted with the antibody.
