unnaturally occurring beta-glycosidase variant, recombinant polynucleotide, vector, host cell, methods for producing at least one unnaturally occurring beta-glucosidase variant for conversion of a glycosyl group-acceptor substrate to a beta-glycosylated product and for transglycosylation of a substrate, and, composition.
JACK LIANG,JONATHAN VROOM,NIKKI DELLAS,RAVI DAVID GARCIA,STEPHANIE SUE GALANIE
申请号:
BR112018075932
公开号:
BR112018075932A2
申请日:
2017.06.09
申请国别(地区):
BR
年份:
2019
代理人:
摘要:
The present invention provides modified β-glycosidase (bgl) enzymes, polypeptides having bgl activity, and polynucleotides encoding these enzymes, as well as host vectors and cells comprising these polynucleotides and polypeptides. The present invention also provides compositions comprising the enzymes, and methods of using the modified bgl enzymes to prepare β-glycosidic bond products.a presente invenção fornece enzimas ß-glicosidase (bgl) modificadas, polipeptídeos tendo atividade de bgl, e polinucleotídeos que codificam estas enzimas, e também vetores e células hospedeiras compreendendo estes polinucleotídeos e polipeptídeos. a presente invenção fornece, outrossim, composições compreendendo as enzimas, e métodos de uso das enzimas bgl modificadas para preparar produtos com ligações ß-glicosídicas.