METHOD FOR PRODUCING OXALATE OXIDASES HAVING ACTIVITY OPTIMUM NEAR PHYSIOLOGICAL PH AND USE OF SUCH RECOMBINANT OXALATE OXIDASES IN THE TREATMENT OF OXALATE-RELATED DISEASES

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专利权人:

发明人:

申请号：

EP14819001.0

公开号：

EP3087178B1

申请日:

2014.12.22

申请国别(地区):

EP

年份:

2018

代理人:

摘要：

Novel oxalate oxidases are provided, which have suitable oxalate degrading activity near physiological pH (7.4). The properties of these OxOx make them potential drug candidates for use in reducing oxalate concentration in patients suffering from excess of oxalate. Especially due to the high activity at physiological pH, the OxOxs are suitable drug candidates for parenteral administration, i.e. to reduce the oxalate concentration in the plasma.

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