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COMPLEXES OF GERMANIUM WITH AMINO ACIDS AND CARBOXYLIC ACIDS AND PROCEDURE FOR THE PREPARATION OF SAME
专利权人:
Obschestvo S Ogranichennoi Otvetstvennostyu "WDS Pharma"
发明人:
ISAEV, Alexandr Dmitrievich,MANASHEROV, Tamaz Omarovich,AMBROSOV, Igor Valerievich,MATELO, Svetlana Konstantinovna
申请号:
DK12866873
公开号:
DK2808330T3
申请日:
2012.11.09
申请国别(地区):
DK
年份:
2017
代理人:
摘要:
The invention relates to complex compounds of germanium with amino acids and carboxylic acids of the general formula Ge[OH] a [AA] b [CA] c (I), where AA is an amino acid, CA is a carboxylic acid, a = 0-3, b = 1-3, c = 0-3, and 1<;b+c<;4, wherein AA and CA in the complex can be identical or different, and to a method for preparing the same. The method consists in preparing an aqueous suspension of germanium dioxide, adding an amino acid and a carboxylic acid to the aqueous suspension of germanium oxide produced, heating the mixture produced with agitation at a temperature of 40-100°C for 2-14 hours with subsequent filtering, removal of the water and production of a complex in solid form. The method makes it possible to prepare stable complex compounds with a controllable composition and a controllable ratio of germanium to amino acid and carboxylic acid which are stable in solid form and can be used in medicine.
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