PROBLEM TO BE SOLVED: To provide a multiplexing stimulation response type polymer that excels in biocompatibility, and that shows a pH and temperature response of high sensitivity, and to provide a method for manufacturing the same.SOLUTION: A multiplexing stimulation response type polymer at least includes: a first side chain having an ionicity functional group and a second side chain having a peptide structure of which the structural unit is an amino acid sequence shown by formula (1). In the formula, X1 and X2 each independently denote an arbitrary α-amino acid residue.COPYRIGHT: (C)2013,JPO&INPIT【課題】生体適合性に優れるとともに、高感度のpH及び温度応答性を示す多重刺激応答型高分子及びその製造方法を提供する。【解決手段】本発明にかかる多重刺激応答型高分子は、イオン性官能基を含む第1の側鎖と、下記(1)で表されるアミノ酸配列を構成単位とするペプチド構造を含む第2の側鎖とを少なくとも有することを特徴とする。【化1】【選択図】 なし