UNIVERSITATEA DE MEDICINĂ ŞI FARMACIE "IULIU HAŢIEGANU" DIN CLUJ-NAPOCA
发明人:
MIHU CARMEN MIHAELA,MIHU CARMEN MIHAELA,ŞORIŢĂU OLGA,ŞORIŢĂU OLGA,RUS CIUCA DAN FLORIN,RUS CIUCA DAN FLORIN,SUSMAN VALERIU SERGIU,SUSMAN VALERIU SERGIU,MIHU DAN,MIHU DAN,IRIMIE ALEXANDRU,IRIMIE ALEXAN
申请号：
RO201000986
公开号：
RO126746B1
申请日:
2010.10.18
申请国别(地区):
RO
年份:
2018
代理人:
摘要：
The invention relates to a method for preparing hepatocytic and pancreatic progenitors to be used in cellular therapy. According to the invention, the method consists in growing stem cells isolated from the chorial or membranous portion of the placenta, in usual laboratory conditions, after which there takes place the expansion of undifferentiated stem cells and characterization thereof, further on they being grown on a collagen substrate, in the presence of a differentiation medium, resulting in a change of cell morphology and three-stage differentiation of placenta mesenchymal stem cells into common hepatic-pancreatic progenitor cells.
