DURRANT STEVEN JOHN,CHARRIER JEAN-DAMIEN,STUDLEY JOHN,PIERARD FRANCOISE YVONNE THEODORA MARIE,LITTLER BENJAMIN JOSEPH,HUGHES ROBERT MICHAEL,SIESEL DAVID ANDREW,URBINA ARMANDO,SHI YI,ANGELL PAUL
申请号：
NZ62308912
公开号：
NZ623089A
申请日:
2012.09.28
申请国别(地区):
NZ
年份:
2016
代理人:
摘要：
The present disclosure relates to processes and intermediates for preparing compounds useful as inhibitors of ATR kinase, such as aminopyrazine-isoxazole derivatives and related molecules. The present disclosure also relates to compounds useful as inhibitors of ATR protein kinase. The disclosure relates to pharmaceutically acceptable compositions comprising the compounds； methods of treating of various diseases, disorders, and conditions using the compounds； processes for preparing the compounds； intermediates for the preparation of the compounds； and solid forms of the compounds. The compounds have formula (I) or (II) wherein the variables are as defined herein.
