A transdermal absorption preparation precursor 50 containing a release liner 10 containing one first valley fold part 1, one or two first mountain fold parts 2, and a first base line L1 and a second base line L2 on one side and the other side apart from the first valley fold part 1 as a line of demarcation and at an approximately equal distance from the first valley fold part 1, wherein at least one of the first base line L1 and the second base line L2 is a fold line of the first mountain fold part 2, and a drug-containing layer 3 having a center line laid on the first base line L1 and an adhesive layer 4 having a center line laid on the second base line L2 on the release liner 10.本發明提供一種含有離型襯墊10之經皮吸收製劑前驅體50,該離型襯墊含有一個第一谷摺疊部分1、一或兩個第一山摺疊部分2及於一側及另一側上與作為分界線之該第一谷摺疊部分1隔開且距離該第一谷摺疊部分1大致相等距離的第一基線L1及第二基線L2,其中該第一基線L1及該第二基線L2中之至少一者為該第一山摺疊部分2之摺疊線;及在該離型襯墊10上具有位於該第一基線L1上之中心線之含藥物層3及具有位於該第二基線L2上之中心線之接著劑層4。1‧‧‧第一谷摺疊部分2‧‧‧第一山摺疊部分3‧‧‧含藥物層4‧‧‧接著劑層5‧‧‧基板層10‧‧‧離型襯墊50‧‧‧經皮吸收製劑前驅體L1‧‧‧第一基線L2‧‧‧第二基線
