Strain of Salmonella enterica s. typhimurium, its use and a method to obtain a therapeutic vaccine vector

• 收藏
• 分享

专利权人:

Joanna Bereta;Paulina Chorobik

发明人:

Michal Bereta,Paulina Chorobik

申请号：

US13148139

公开号：

US08916372B2

申请日:

2010.02.23

申请国别(地区):

US

年份:

2014

代理人:

摘要：

The present invention relates to a new bacterial strain of Samonella enterica serovar Typhimurium VNP20009 deposited in the Polish Collection of Microorganisms under access no. B/00024 and its us in the production of a vaccine, especially an anti-cancer vaccine. The present invention also relates to a method of obtaining a therapeutic vaccine vector, characterized in that a genetic modification is introduced into the vector strain specific to cancer cells, resulting in the delayed over expression of a gene encoding a protein responsible for the invasive ability of this strain.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/