In a method and an apparatus to exam a tissue sample, a female breast is compressed in an x-ray imaging apparatus and a biopsy procedure is conducted to extract a tissue sample from the compressed breast, with the extraction taking place using images generated by the x-ray imaging system. While the breast is still compressed, the extracted tissue sample is transported to a region outside of the extraction location that is irradiated by x-rays from the x-ray source of the imaging apparatus, and is irradiated at that region by the x-ray source in order to generate 3D data from a radiation detector that are used to reconstruct a data set of slice images from common projections of the extraction region and the tissue sample. The reconstructed slice images are then displayed.
