Simon N. Pettit,Andrew D. Jones,Catherine Simone V. Frydrych,Alex J. Thomas,Michael E. Garst
申请号：
US15831681
公开号：
US20180094031A1
申请日:
2017.12.05
申请国别(地区):
US
年份:
2018
代理人:
摘要：
The present invention relates to cyclosporin analogs that are potent inhibitors of cyclophilin D and have low immunosuppressive activity processes for preparing them pharmaceutical compositions containing them and methods for using these analogs and compositions containing them for the treatment of medical conditions, including but not limited to ischemic conditions, such as ischemia-reperfusion (I/R) injury, including myocardial FR injury, cerebral I/R injury, and ocular or retinal I/R injury.
