The present invention relates to an improved patient monitoring device. The device comprises a modular enclosure, a controller means positioned inside said enclosure converting various physiological signals into their corresponding digital forms, plurality of detachable plug-in modules receiving various physiological signals from a target body and transferring said signals to said controller means, plurality of detachable sensor cable means sensing various physiological signals from the target body and transferring them to the plug-in module, input means and output display means operatively connected with said controller means placed on the front side of said enclosure means. The device automatically senses the various types of sensor cables connected and disconnected and accordingly reformat and adjust the display screen to assist the caregiver to provide speedy service.