PURPOSE: A method for manufacturing a sustained-release tablet, which is able to simply manufacture the sustained-release tablet with reproducibility is provided to stably control release patterns using a general apparatus for manufacturing a tablet. CONSTITUTION: A sustained-release tablet comprises a tablet, a primary sustained release coating layer, and a secondary sustained release coating layer. The tablet contains a drug as an active ingredient. The primary sustained release coating layer is made of a sustained release polymer materials formed on the tablet. The secondary sustained release coating layer is made of a mixture of the sustained release polymer material and a drug as an active ingredient. A method for manufacturing the sustained release tablet comprises: a step of mixing the drug and a primer binder； a step of sieving the mixture without mass, binding with a binding solution, drying, and tableting； a step of mixing with a secondary binder； a step of adding a lubricant and tableting to prepare a tablet； a step of uniformly dissolving the surface of the tablet with a dissolution agent and coating to form the primary sustained release coating layer； and a step of uniformly dissolving the coated tablet, adding the drug, and coating. [Reference numerals] (AA) Methylphenidate HCl elution rate(%)； (BB) Elution rate(%)본 발명은 일반적인 정제 제조장치를 사용하여 방출 패턴을 안정적으로 제어한 서방성 정제 및 제조공정이 단순하고 재현성 있는 제조가 가능한 서방성 정제의 제조방법에 관한 것으로서, 본 발명은 매트릭스 정제를 제조한 후 1차 코팅층으로 서방성 고분자물질층을 형성하고 약물과 고분자물질로 2차 코팅층이 되도록 설계된 것을 특징으로 한다.
