Access, or injection ports, are disclosed. These are shown with various needle-penetrable sealing septums. The septum design is shown with a first and second (and optionally more) elastomeric regions. Indicia may be formed in at least one of said regions, by voids or otherwise and medical imaging additive may be used to provide radiopaque or other contrast between said regions to provide indicia. Such elements may include where two or more such regions are over-molded. The indicia may be on or embedded in the septum. Methods of making such septums and/or ports, including blending and molding is disclosed.
