Glickman, Michael,Jiang, Xuejun,Barkan, Daniel,Redelman-Sidi, Gil,Iyer, Gopa,Solit, David,Bochner, Bernard H.
申请号：
AU2013299643
公开号：
AU2013299643A1
申请日:
2013.08.07
申请国别(地区):
AU
年份:
2015
代理人:
摘要：
Bacillus Calmette-Guerin (BCG) administration plays a central role in managing carcinoma in situ of the bladder. Unfortunately, recurrence or progression of disease is seen in up to 30% of treated patients. Disclosed herein is a method for predicting responsiveness to treatment with BCG based on BCG internalization by bladder cancer cells, the presence or absence of mutations associated with BCG uptake or a combination thereof.
