SUN, Jeonghoon,TAM, Lei-ting Tony,HAN, Hq,KWAK, Keith Soo-nyung,ZHOU, Xiaolan
申请号:
LT08742032
公开号:
LT2132314T
申请日:
2008.03.06
申请国别(地区):
LT
年份:
2017
代理人:
摘要:
The present invention provides variant activin IIB soluble receptor polypeptides and proteins capable of binding and inhibiting the activities of activin A, myostatin, or GDF-11. The present invention also provides polynucleotides, vectors and host cells capable of producing the variant polypeptides and proteins. Compositions and methods for treating muscle-wasting and other diseases and disorders are also provided.