БАЛА Хани (IN),ХАСИДЖА Рахул (IN),ЧАУХАН Сатиш Кумар (IN),БАХРИ Дипак (IN)
申请号：
RU2010128222/15
公开号：
RU2010128222A
申请日:
2008.10.07
申请国别(地区):
RU
年份:
2012
代理人:
摘要：
1. An ophthalmic composition comprising phenylephrine, a viscoelastic substance, an osmotic substance, a buffer substance and water. ! 2. The composition according to claim 1, in which the content of phenylephrine is in the range from 0.15% to 10% weight to volume ratio. ! 3. The composition according to claim 1, in which phenylephrine is a salt selected from the group comprising hydrochloride, bicarbonate, sulfate, nitrate, tartarate and acetate. ! 4. The composition according to claim 1, in which the viscoelastic substance is selected from the group comprising carboxymethyl cellulose, polyvinyl alcohol, hydroxypropyl methyl cellulose, hydroxyethyl cellulose, povidone and dextran. ! 5. The composition according to claims 1 and 4, in which the viscoelastic substance is hydroxypropylmethyl cellulose. ! 6. The composition according to claim 1, in which the content of viscoelastic substance is in the range of 0.1-3%, preferably 0.2-1% and most preferably 0.2-0.5%. ! 7. The composition according to claim 1, in which the viscosity of the composition is in the range of 0.1-10 sp. ! 8. The composition according to claim 1, in which the viscosity of the composition is in the range of 0.5-5 sp. ! 9. The composition according to claim 1, in which the viscosity of the composition is in the range of 1-3 cP. ! 10. The composition according to claim 1, in which the osmotic substance is selected from the group comprising salt and sugar. ! 11. The composition of claim 10, in which the salt is selected from the group comprising a cation of sodium, potassium or ammonium, and the anion of chloride, citrate, ascorbate, borate, phosphate, bicarbonate, sulfate, thiosulfate or bisulfate. ! 12. The composition of claim 10, in which the sugar is selected from the group comprising dextrose, lactose, xylitol, mannitol and glycerin. ! 13. The composition of claim 10, in which the osmotic substance is selected from the group comprising sodium chloride, potassium chloride, sodium thiosulfate1. О
