A cannula assembly for directing blood from the heart of a patient and a minimally invasive method of implanting the same. The cannula assembly includes a flexible cannula body (310) having a proximal end and a distal end with a receiving portion, and a transseptal tip (186) having a distal end and a proximal end with an engaging portion. First and second anchors (202, 206) are coupled to the transseptal tip (186) and configured to be deployed from a contracted state to an expanded state. The engaging portion (198) of the transseptal tip (186) is operable to removably engage the receiving portion of the flexible cannula body (310) in vivo.