Bradley E. Bernstein,Jon C. Aster,James E. Bradner,Birgit Knoechel,Christopher J. Ott,David Root
申请号:
US14409138
公开号:
US09763956B2
申请日:
2013.06.19
申请国别(地区):
US
年份:
2017
代理人:
摘要:
The invention relates to methods of treatment and diagnosis of subjects with cancer. In some aspects, the invention relates to methods of treatment and diagnosis of subjects with cancer, wherein the cancer is characterized by a Notch pathway activation mutation or by resistance to a Notch pathway inhibitor.