Mirna and its diagnostic and therapeutic uses in diseases or conditions associated with melanoma, or in diseases or conditions associated with activated braf pathway
INTERNA TECHNOLOGIES BV;KONINKLIJKE NEDERLANDSE AKADEMIE VAN WETENSCHAPPEN
发明人:
BEREZIKOV EUGENE,POELL JOS BERNARD,GOMMANS WILLEMIJN MARIA,VAN HAASTERT RICK JAN,VAN PUIJENBROEK ANDREAS ALPHONS FRANCISCUS LUDOVICUS,SCHAAPVELD ROELAND QUIRINUS JOZEF,PREVOST GRÉGOIRE PIERRE ANDRÉ
申请号：
NZ60542011
公开号：
NZ605420A
申请日:
2011.07.01
申请国别(地区):
NZ
年份:
2015
代理人:
摘要：
Disclosed is a use of a miRNA-3157 molecule, a miRNA molecule from 6 to 30 nucleotides in length comprising at least 6 of the nucleotides present in seed sequence SEQ ID NO: 173 and/or having at least 70% identity with SEQ ID NO:112, an isomiR, or a source thereof or a composition comprising said miRNA, isomiR, or source thereof in the manufacture of a medicament for preventing, treating, regressing, curing and/or delaying a disease or a condition associated with melanoma and/or a disease or a condition associated with activated BRAF pathway, wherein the miRNA molecule and sequences are as defined in the complete specification
