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PATCH
专利权人:
Hiroko Udagawa;Masaru Hamabe;Sakiko Shibata;Toshikazu Komoda
发明人:
Hiroko Udagawa,Toshikazu Komoda,Sakiko Shibata,Masaru Hamabe
申请号:
US13976647
公开号:
US20130287823A1
申请日:
2010.12.28
申请国别(地区):
US
年份:
2013
代理人:
摘要:
Disclosed is a patch excellent in storage stability and transdermal absorbability of midodrine and having good adhesion. The patch includes a backing and a medicated layer stacked on one surface of the backing so as to be integrated with the backing. The medicated layer contains 3 to 40% by weight of midodrine and 60 to 97% by weight of an acrylic adhesive including a copolymer formed by copolymerization of monomers including 60 to 98% by weight of an alkyl acrylate having an alkyl group with 1 to 12 carbon atoms and 2 to 40% by weight of 1-vinyl-2-pyrrolidone. In the medicated layer, part of midodrine is present in an undissolved state.
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