Methods of making a coating on a medical device are disclosed, includingassociating a composition with at least a portion of the device to form alayer. In some embodiments, a composition may include a copolymer preparedfrom a room temperature melt of a plurality of monomer units that comprises afirst monomer unit and a second monomer unit, wherein the second monomer unithas a glass transition temperature that is at least about 30 degreesCentigrade higher than the glass transition temperature of the first monomerunit, with a glass transition temperature of a monomer unit being defined as aglass transition temperature of a homopolymer of that monomer unit.
