The present invention relates to an extract of chelidonium majus extracted at high pressure and high temperature, and a water tissue containing a distillate thereof; and more specifically, to an extract of chelidonium majus extracted at a high pressure of 1.2-2.8 atm and a high temperature of 120-131°;C and a water tissue containing a distillate thereof. The extract of chelidonium majus and the water tissue containing a distillate thereof can be used for skin cleansing and treating inflammatory diseases because the extract of chelidonium majus and water tissue containing the distillate thereof have excellent antibacterial and antifungal properties against pathogenic microorganisms residing on skin, and excellent inflammation inhibiting effects, cleansing effects, washing effects, disinfection effects to bug bites, atopy treating effects, and gash treating effects. [Reference numerals] (AA) (First process) Step for manufacturing an extract of chelidonium majus by mixing 100 parts by weight of chelidonium majus with 2000 to 8000 parts by weight of water and extracting chelidonium majus at a high pressure of 1.2-2.8 atm and a high temperature of 120-131째C; (BB) (Second process) Step for absorbing the extract of chelidonium majus into a fabric for a water tissue by spraying 200 to 400 parts by weight of the extract of chelidonium majus, which has been manufactured in the first process to 100 parts by weight of the fabric for a water tissue; (CC) (Third process) Step for manufacturing a water tissue containing the extract of chelidonium majus by sealing and sterilizing the fabric for a water tissue having the extract of chelidonium majus absorbed therein본 발명은 고온 고압 조건에서 추출한 백굴채 열수 추출물 또는 이의 증류액을 함유하는 물티슈에 관한 것으로서, 보다 자세하게는 120~131℃ 및 1.2~2.8기압의 고온 고압 조건에서 추출한 백굴채 열수 추출물 또는 이의 증류액을 함유하는 물티슈에 관한 것이다. 상기 백굴채 열수 추출물 또는 이의 증류액을 함유하는 물티슈는 피부에 상재하는 병원성 미생물에 대해서 항균성 및 항진균성이 뛰어나고 염증 억제 효과, 세정 효과, 세척 효과, 벌레물린데의 소독 효과, 아토피 치료 효과, 창상 치료 효과 등이 우수하여, 피부 청결 및 각종 염증 질환의 개선에 용이하게 이용될