The present invention relates to generating a film suitable for medical packaging. The film is generated by blown film co-extrusion to form a multi-layer film which has a heat resistant layer, a barrier layer and a heat seal layer. The barrier layer includes a high barrier resin and a branched co-polymer. The high barrier resin has a density of at least 0.963 g/cm3. The barrier layer includes between 25% and 85% high barrier resin. The heat resistant layer may be comprised of polymers, papers and other materials. The heat seal layer, in some embodiments, comprises any of high density polyethylene and medium density polyethylene, or a combination thereof. In some embodiments, an additional laminate layer may be affixed to the heat resistant layer of the multi-layer film. The final film is between 3.0 and 3.8 mils in thickness, and has a moisture vapor transmission rate of less than 0.08.