Whiteker, Gregory T.,Borromeo, Peter,Li, Fangzheng,Roth, Gary
申请号：
AU2017209455
公开号：
AU2017209455A1
申请日:
2017.01.23
申请国别(地区):
AU
年份:
2018
代理人:
摘要：
4-Alkoxy-3-hydroxypicolinic acids may be conveniently prepared from 4,6-dibromo-3-hydroxypicolinonitrile in a series of chemical steps selected from bromo substitution, nitrile hydrolysis and halogen reduction that are conducted as a single pot process. 4,6-Dibromo-3-hydroxypicolinonitrile may be prepared from furfural in a series of chemical steps selected from cyano-amination, amine salt formation and bromination-rearrangement. 4-Alkoxy-3-acetoxypicolinic acids may be conveniently prepared from 4-alkoxy-3-hydroxypicolinic acids by treatment with acetic anhydride.
