LANGGUTH, THOMAS,DITTGEN, MICHAEL,HUBER, PETRA,SCHENK, DIRK,BRACHT, STEFAN
申请号:
DK09173898
公开号:
DK2138169T3
申请日:
2004.12.10
申请国别(地区):
DK
年份:
2013
代理人:
摘要:
The present invention relates to a patch comprising a drug-containing layer with low content of hormones, such as gestodene, and optionally an estrogen (e.g. ethinyl estradiol). Upon administering the patch to a woman, plasma levels of at least 1.0 ng/ml of Gestodene is achieved at steady state conditions without the need of incorporating penetration enhancers or permeation enhancers in the drug-containing layer. Satisfactorily plasma levels of the hormones is also achieved throughout a period of at least 1 week, making the patch applicable for being used in female contraception with the concept of administering the patch ones weekly. <;IMAGE>;