#$%^&*AU2017208298A120170817.pdf#####ABSTRACT The teachings provided herein generally relate to site-activated binding systems that selectively increase the bioactivity of phenolic compounds at target sites. The systems can include a phenolic compound bound to a reactive oxygen species, wherein the phenolic compound and the reactive oxygen species can react at a target area in the presence of an oxidoreductase enzyme. The systems can be used, for example, as an antitoxin, an antiinflammatory, or an antimicrobial. Uses can include treatment of a gastrointestinal condition, a damaged dermal tissue, or a damaged mucosal tissue, as well as in promoting gastrointestinal health that can, for example, result in alleviating gastrointestinal discomfort or, perhaps, creating a weight gain in an animal.WO 2012/178127 PCT/US2012/043900 Grazix Growth Promotion Post Wean, 35 Days 9 Grazia ,8.05 kg 7U Control, 6A1 kg Control, n=8 Runts 5.6 kg 5 m GGrazix, n2 E 4 Unereght 0.30 0.22 02 3 1 -.0 Base Wkl Wk2 Wk3 Wk4 Wk5 FIG. 1A 1/13