Transgenic clawed frog embryos and use thereof as detectors of endocrine disrupters in the environment

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专利权人:

Barbara Demeneix

发明人:

Barbara Demeneix,Nathalie Turque

申请号：

US10516134

公开号：

US08476484B2

申请日:

2003.05.27

申请国别(地区):

US

年份:

2013

代理人:

摘要：

The invention relates to transgenic aquatic animals, particularly the clawed frog and the zebra fish and cells derived therefrom, characterized in comprising at least one expression cassette with a regulatory DNA sequence selected from the response elements to nuclear hormone receptors, particularly TRE, connected in a functional manner downstream of a DNA segment coding for a marker protein such as luciferase or GFP. The invention further relates to methods using the transgenic cells and animals according to the invention for the identification of endocrine disrupters in the environment.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/