John David Lawson,Mark Sabat,Christopher Smith,Haixia Wang,Young K. Chen,Toufike Kanouni
申请号：
US14381187
公开号：
US20150038510A1
申请日:
2013.03.25
申请国别(地区):
US
年份:
2015
代理人:
摘要：
Disclosed are compounds of Formula 1,and pharmaceutically acceptable salts thereof, wherein R1, R2, R3, R4, and R5 are defined in the specification. The compounds are inhibitors of Bruton's tyrosine kinase (BTK). This disclosure also relates to materials and methods for preparing compounds of Formula 1, to pharmaceutical compositions which contain them, and to their use for treating diseases, disorders or conditions associated with BTK.
