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Metronomic convection enhanced delivery of intrathecal chemotherapy using an implanted magnetic breather pump (MBP) for leptomeningeal carcinomatosis
专利权人:
Yehoshua Shachar
发明人:
Yehoshua Shachar,Thomas C. Chen,Leslie Farkas,Bruce Marx,David Johnson,Laszlo Farkas
申请号:
US12581756
公开号:
US08323269B2
申请日:
2009.10.19
申请国别(地区):
US
年份:
2012
代理人:
摘要:
A magnetically controlled pump is implanted into the cerebrospinal fluid of a patient and delivers a plurality of medicating agents at a controlled rate corresponding to the specific needs of the patient. The current invention comprises a flexible double walled lumen, intratumoral catheter which will be implanted. Spinal fluid drawn from the patient is analyzed. Medication is delivered on a continuous metronomic basis into the CSF via an internalized pump. CSF is removed and analyzed for VEGF and other cytokines via spectrophotometer analysis or a lab on a chip. The operation of the apparatus and hence the treatment is remotely controlled based on these measurements and displayed through an external controller.
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中国工程科技知识中心
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