Compounds, pharmaceuticals, kits and methods are provided for use with DPP-IVand other S9 proteases that comprise a compound comprising Formula (I):STR1 wherein M is N or CR4; Q1 and Q2 are each independently selected fromthe group consisting of CO, SO, SO2, and C=NR9; and each R1, R2, R3, R4 and R9are as defined herein.