Peters, Perry,Van Kammen, Daniel,Brann, Mark,Bahr, Daun,Furlano, David
申请号:
AU2008228833
公开号:
AU2008228833B2
申请日:
2008.03.19
申请国别(地区):
AU
年份:
2013
代理人:
摘要:
Combinations of 5-HT2A inverse agonists or antagonists such as pimavanserin withantipsychotics such as risperidone are shown to induce a rapid onset of antipsychotic actionand increase the number of responders when compared to therapy with the antipsychoticalone. These effects can be achieved at a low dose of the antipsychotic, therebyreducing the incidence of side effects. The combinations are also effective atdecreases the incidence of weight gain and increased glucose or prolactin levelscaused by the antipsychotic.