A body (12), comprising at least one compartment for containing at least one lower volume of 5 ml of pharmaceutical solvent (22) a head (14), comprising at least one compartment for containing at least one active principle (24), particularly a very low dose, and comprising, in the upper portion thereof, of at least one collection chamber (32) provided with a filter (40), said head (14) capable of taking a first storing position £1, wherein said head (14) is in a distal position relative to the body (12), and a second preparation position P2, wherein said head (14) is in a proximal position relative to the body (12), at least one partition (16) separating the body (12) and the head (14) and a rupturing means (18) for rupturing said partition (16) such that the active principle (24) comes into contact with the solvent (22) and dissolves into the latter. The invention also aims to use said device to store and extemporaneously prepare at least one active principle with a view to administer the same.