Shanghai Hengrui Pharmaceutical Co., Ltd.;Jiangsu Hengrui Medicine Co. Ltd.
发明人:
申请号:
EP18739200.6
公开号:
EP3569596A1
申请日:
2018.01.12
申请国别(地区):
EP
年份:
2019
代理人:
摘要:
The present invention relates to a 1,2,4-triazine-3-amine derivative, a preparation therefor, and use thereof in medicine. Specifically, the present invention relates to a 1,2,4-triazine-3-amine derivative as represented by general formula (I), a preparation method therefor, a pharmaceutical composition comprising the derivative, and use thereof as a therapeutic agent, in particular as an A2a receptor antagonist, and use thereof in the preparation of a medicament for treating a condition or disorder that is ameliorated by means of inhibition of the A2a receptor, each substituent in general formula (I) being same as defined in the description.