The objective of the present invention is to provide an extract from inflamed rabbit skin inoculated with vaccinia virus and formulations, etc. including the extract which have greater uniformity in quality. By using the amount of N-acetyl neuraminic acid contained in the extract from inflamed rabbit skin inoculated with vaccinia virus and the formulations including the extract as an index, greater uniformity of the extract and the formulations can be ensured for each production lot. The extract from inflamed rabbit skin inoculated with vaccinia virus and the formulations including the extract, which are produced in this manner so as to have greater uniformity, are extremely useful with effectiveness and safety more rigorously secured.