COLEY PHARMACEUTICAL GMBH;UNIVERSITY OF IOWA RESEARCH FOUNDATION
发明人:
ARTHUR M. KRIEG,JORG VOLLMER,EUGEN UHLMANN
申请号：
SG2006010128
公开号：
SG177000A1
申请日:
2002.08.19
申请国别(地区):
SG
年份:
2012
代理人:
摘要：
AbstractCOMBINATION MOTIF IMMUNE STIMULATORY OLIGONUCLEOTIDES WITH IMPROVED ACTIVITYA class of immunostimulatory nucleic acids having at least two functionally and structurally defined domains is provided. This class of combination motif immunostimulatory nucleic acids activates an immune response and is useful for treating a variety of immune realted disorders such as cancer, infectious disease, and allergic disorders. The nucleic acids also stimulate activation of natural killer cells and production of type 1 interferon.Fig. 1
