HU, CHE MING,胡哲铭,胡哲銘,CHEN, HUI WEN,陈慧文,陳慧文,YAO, BING YU,姚秉瑜,姚秉瑜
申请号：
TW106109510
公开号：
TW201804989A
申请日:
2017.03.22
申请国别(地区):
TW
年份:
2018
代理人:
摘要：
A polymeric nanoparticle that has a size of 30 - 600 nm in outer diameter and contains a polymeric shell, less than 25 nm in thickness and impermeable to water, one or more aqueous cores enclosed by the polymeric shell, and a bioactive agent encapsulated in each of the one or more aqueous cores. Also disclosed are a method of preparing the polymeric nanoparticle and a method of using it for treating a disease.本發明揭露一種聚合物奈米粒子,其外直徑之尺寸為30-600nm,且含有厚度少於25nm且不透水的聚合物殼、一或多個由該聚合物殼封閉之含水核,以及包覆於每一該一或多個含水核中的生物活性劑。本發明亦揭露一種製備該聚合物奈米粒子之方法及一種使用其治療疾病之方法。
