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PORPHYRIN MODIFIED TELODENDRIMERS
专利权人:
THE REGENTS OF THE UNIVERSITY OF CALIFORNIA
发明人:
Kit S. LAM,Yuanpei LI,Chong-Xian PAN
申请号:
US16355123
公开号:
US20200046841A1
申请日:
2019.03.15
申请国别(地区):
US
年份:
2020
代理人:
摘要:
The present invention provides amphiphilic telodendrimers that aggregate to form nanocarriers characterized by a hydrophobic core and a hydrophilic exterior. The nanocarrier core may include amphiphilic functionality such as cholic acid or cholic acid derivatives, and the exterior may include branched or linear poly(ethylene glycol) segments. Nanocarrier cargo such as hydrophobic drugs and other materials may be sequester in the core via non-covalent means or may be covalently bound to the telodendrimer building blocks. Telodendrimer structure may be tailored to alter loading properties, interactions with materials such as biological membranes, and other characteristics.
来源网站:
中国工程科技知识中心
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http://www.ckcest.cn/home/

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