ALTON, Eric Walter Frederick Wolfgang,GRIESENBACH, Uta,PYTEL, Kamila Malgorzata,PAUL-SMITH, Michael Christian,PRINGLE, Ian Andrew,HYDE, Stephen Charles,GILL, Deborah Rebecca,DAVIES, Lee Adrian,BOYD, A
申请号:
DK15720762
公开号:
DK3145949T3
申请日:
2015.04.23
申请国别(地区):
DK
年份:
2020
代理人:
摘要:
This invention relates to lentiviral gene transfer vectors pseudotyped with hemagglutinin-neuraminidase (HN) and fusion (F) proteins from a respiratory paramyxovirus, comprising a promoter and a transgene; and methods of making the same. The present invention also relates to the use of said vectors in gene therapy, particularly for the treatment of respiratory tract diseases such as Cystic Fibrosis (CF).