Timothy HAGEN;Mark E. GURNEY;Munagala RAO;Jasbir SINGH;Alex BURGIN;Alexander KISELYOV
发明人:
Jasbir SINGH,Mark E. GURNEY,Alex BURGIN,Alexander KISELYOV,Munagala RAO,Timothy HAGEN
申请号:
US13457716
公开号:
US20120213758A1
申请日:
2012.04.27
申请国别(地区):
US
年份:
2012
代理人:
摘要:
The present invention relates to a genus of biaryl compounds containing at least one further ring. The compounds are PDE4 inhibitors useful for the treatment and prevention of stroke, myocardial infarct and cardiovascular inflammatory diseases and disorders. The compounds have general formula Ia, Ib, Ic or Id:A particular embodiment is